The path to research success includes many ups and downs and can take you to unexpected places. On September 25th, 2019, Queen’s University hosted the Nobel Prize Inspiration Initiative, featuring Martin Chalfie, 2008 Nobel Laureate in Chemistry. In a public dialogue moderated by preeminent journalist, André Picard, Dr. Chalfie was joined by Queen’s researcher Dr. Arthur McDonald, 2015 Nobel Laureate in Physics, and Dr. Mona Nemer, Chief Science Advisor to the Government of Canada, to discuss the path to the Nobel Prize and research success. The event provided a unique and exclusive opportunity for students, researchers, and community members to interact with some of the most recognized members of the international research community.