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BIOL 432  Computation and Big Data in Biology  Units: 3.00  
Application of basic coding and analytical methods to obtain, organize, analyze, visualize, and interpret information from large, complex datasets (i.e. 'Big Data') in biology. Datasets may include climate/weather records, 'omics' data, specimen collections, long-term observational studies, journal articles, and other historical and online sources.
Learning Hours: 120 (36 Lecture, 12 Tutorial, 72 Private Study)  
Requirements: Prerequisite BIOL 343/3.0 and a minimum GPA of 2.0 in the Biological Foundations List.  
Offering Faculty: Faculty of Arts and Science  

Course Learning Outcomes:

  1. Analyze data commonly used in genomics (e.g. FASTA, FASTQ, SAM, BED, BAM) to answer biological questions.
  2. Apply regular expressions to manipulate biological data.
  3. Create publication-ready visualizations of biological data.
  4. Design and implement a strategy for project management in biological research, based on the philosophy that scientific research should be OPEN and REPRODUCIBLE.
  5. Write custom scripts to curate, merge, subset, reformat, and parse large biological datasets.
  6. Write programs for 'big data' in biology, using high-performance computing infrastructure maintained by Queen's Centre for Advanced Computing.