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BCHM 432 The Molecular Basis of Cellular Function Units: 3.00
Principles of regulatory mechanisms; regulation of cellular function and growth by oncogenes, growth factors, isoprenoids and steroid hormones. Receptors, second messengers and protein phosphorylation. Correlation of cell ultrastructure with biochemical function. Description of the components, assembly, metabolism and evolution of cellular structures are described.
Learning Hours: 120 (30 Lecture, 6 Group Learning, 84 Private Study)
Requirements: Prerequisite ([Level 4 or above and registration in the BCHM Specialization or Major Plan] and [a minimum GPA of 2.50 in BCHM 218/3.0; BCHM 313/3.0; BCHM 315/3.0; BCHM 316/3.0; BCHM 317/6.0]) or ([Level 4 or above and registration in the LISC Specialization or Major Plan] and [a minimum GPA of 2.50 in BCHM 218/3.0 and [BCHM 310/9.0 or [BCHM 315/3.0 and BCHM 316/3.0]).
Offering Faculty: Faculty of Health Sciences
Course Learning Outcomes:
- The primary objective of this course is to provide students with a basic understanding of the major signaling pathways that regulate important cell functions such as growth, proliferation, survival and motility.
- Emphasis will be placed on the biochemical properties, including structure and enzymatic activity, of key signaling enzymes such as protein kinases, ubiquitin ligases, G protein coupled receptors and the enzymes that synthesize leukotrienes and prostaglandins.