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Queen's University


brisbinNew research from the Chin-Sang lab reveals novel antagonism between Eph receptor tyrosine kinase & PTEN tumor suppressor genes in C. elegans

Sarah Brisbin (M.Sc. Chin-Sang Lab) et al. show that in C. elegans, the Eph receptor tyrosine kinase (RTK) and the tumor suppressor PTEN are mutually inhibitory. This antagonism influences germline and longevity-related functions. These data suggest possible modes of crosstalk between Eph RTKs and PTEN signaling in human cancers. Their article was published in Developmental Cell 20 Oct and can be accessed | here |. See feature of this article in Science Magazine's Editor's Choice!

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